Health & Fit Women with advanced breast cancer are surviving longer, study says

20:28  18 may  2017
20:28  18 may  2017 Source:   The Washington Post

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The study involved 97 women with advanced breast cancer who had a mean age of 55 years. "There are effective treatments for sleep disruption in the general population, and some of them have shown to be effective in cancer survivors as well," said Palesh.

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A radiologist in Wichita Falls, Tex., compares a conventional mammogram with a 3-D digital mammogram. On Thursday, researchers reported that the number of women living with advanced breast cancer is growing substantially, partly due to improved survival.© Torin Halsey/Times Record News via Associated Press A radiologist in Wichita Falls, Tex., compares a conventional mammogram with a 3-D digital mammogram. On Thursday, researchers reported that the number of women living with advanced breast cancer is growing substantially, partly due to improved survival. Increasing survival rates of women with metastatic disease reflect improved treatments, researchers found.

The number of women living with advanced breast cancer is rising substantially in the United States, reflecting improved survival among all ages, according to a study published Thursday.

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American women diagnosed with advanced , stage 4 breast cancer have a better chance of survival , and are surviving longer , compared to two decades ago, a new study Experts said that the value of surgically removing a breast when the cancer has already spread beyond it is still being debated.

The study involved 97 women with advanced breast cancer who had a mean age of 55 years. "There are effective treatments for sleep disruption in the general population, and some of them have shown to be effective in cancer survivors as well," said Palesh.

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The study found that between 1992 and 1994, and 2005 and 2012, the five-year survival rate among women under age 50 initially diagnosed with advanced disease doubled from 18 percent to 36 percent. The median survival time for that group increased from 22.3 months to almost 39 months. For women ages 50 to 64, the survival time grew from a little more than 19 months to almost 30 months.

The lead author, Angela Mariotto of the National Cancer Institute, called the findings “favorable” because they were partly due to longer survival times resulting from better treatments. For example, the drug Herceptin, which was approved in the late 1990s, has been shown to lengthen the lives of women with certain aggressive breast cancers.

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(Reuters Health) - More young women are being diagnosed with advanced , metastatic breast cancer than were three decades ago, a new study suggests - although the overall rate of cancers in that group is still small. One in 173 women will develop breast cancer before she turns 40, researchers said

Combinations of drugs could impede advanced breast cancer tumors in different ways, two large studies suggest. Scientists cautioned that the data so far show only that the patients survived longer before their tumor advanced in size.

The researchers calculated that more than 154,000 women are currently living with cancer that has spread beyond the breast, the most serious form of the disease.

Mariotto, who is chief of the Data Analytics Branch in the NCI's Division of Cancer Control and Population Sciences, said the study didn't explore why younger women survived longer, but one possibility was that they received more aggressive treatment.

Patients with Stage 4 breast cancer — the most advanced — have the most intensive health-care needs, and advocacy groups, providers and researchers are increasingly interested in knowing how many are affected. The study estimated that the number rose by 4 percent from 1990 to 2000 and by 17 percent from 2000 to 2010. From 2010 to 2020, it is projected to increase by almost a third.

Metastatic breast cancer once was considered an immediate death sentence, and it's still largely incurable, the researchers said. But new therapies targeting the triggers of the disease as well as improved palliative care mean women “can and often do live for years with reasonable quality of life, albeit undergoing constant treatment to keep their disease under control,” they said.

The authors, who included researchers at Fred Hutchinson Cancer Research Center in Seattle and the Metastatic Breast Cancer Alliance, said the study was the first to estimate how many women are living with advanced disease in the United States. Their findings appeared online in Cancer Epidemiology, Biomarkers & Prevention.

To calculate the number of women with metastatic breast cancer, the scientists combined the number of women who were initially diagnosed with advanced disease with those who developed it after being diagnosed at an earlier stage. Such estimates are challenging, they said, because of data gaps in cancer registries.

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